When was bpa added to plastic
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Use the browser controls to adjust the font size, or print this page. Further Reading. Fact Sheets 2 pages. This content is available to use on your website. The review was documented in four memoranda and their attachments:. Strong consumer and scientific interest in the safety of BPA has prompted FDA to support additional studies to provide further information and address apparent inconsistencies in the scientific literature about BPA.
Many of these studies addressed how the body disposes of or metabolizes BPA. These studies also addressed questions about how long it takes for the body to dispose of BPA.
Found evidence in rodent studies that the level of the active form of BPA passed from expectant mothers to their unborn offspring, following oral exposure, was so low it could not be measured. The study orally dosed pregnant rodents with times more BPA than people are exposed to through food, and could not detect the active form of BPA in the fetus 8 hours after the mother's exposure.
This results in much lower internal exposure of BPA i. Found that primates including humans of all ages effectively metabolize and excrete BPA much more rapidly and efficiently than rodents. Developed physiologically based pharmacokinetic models that can be used to predict the level of internal exposure to the active and inactive forms of BPA.
Recently completed a rodent subchronic study [ 7 ] intended to provide information that would help in designing a long-term study that is now underway see below. The subchronic study was designed to characterize potential effects of BPA in a wide range of endpoints, including prostate and mammary glands, metabolic changes, and cardiovascular endpoints.
The study included an in utero phase, direct dosing to pups to mimic bottle feeding in neonates, and employed a dose range covering the low doses where effects have been previously reported in some animal studies, as well as higher doses where estrogenic effects have been measured in guideline oral studies.
The results of this study showed no effects of BPA at any dose in the low-dose range. Rodent chronic toxicity study , which is currently underway. As an addition to this core study, FDA is providing extra animals and tissues to a consortium of grantees [ 8 ] selected and funded by the National Institute of Environmental Health Sciences to address other critical questions.
Back to Top. FDA has amended its regulations to no longer provide for the use of BPA-based polycarbonate resins in baby bottles and sippy cups. The ACC petition demonstrated, from publicly available information and information collected from industry sources, that the use of polycarbonate resins in baby bottles and sippy cups had been abandoned.
FDA has amended its regulations to no longer provide for the use of BPA-based epoxy resins as coatings in packaging for infant formula.
This petition demonstrated, from publicly available information and information collected from industry sources, that the use of BPA-based epoxy resins as coatings in packaging for infant formula had been abandoned.
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